Psoriasis Awareness Month: What is psoriasis?

Psoriasis affects more than 3% of the US adult population. That is more than 7.5 million US adults.* Psoriasis is a skin disease that causes a rash with itchy, scaly patches, most commonly on the knees, elbows, body, and scalp. It causes inflammation in the body. There may be visible signs of inflammation such as raised plaques and scales on the skin.

Psoriasis is a chronic disease with no known cure. It can be painful, interfere with sleep, and make it hard to concentrate. The condition tends to go through cycles, flaring for a few weeks or months, then subsiding for a while. Common triggers in people with a genetic predisposition to psoriasis include infections, cuts or burns, and certain medications.

Other organs and tissues may be impacted by the inflammation caused by psoriasis. One in three people with psoriasis may also develop psoriatic arthritis. Signs of PsA include swelling, stiffness and pain in the joints and areas surrounding the joints.**

Psoriasis is not only a skin disease; it may also cause anxiety, and depression, and can increase the risk of heart disease and stroke. It can also be associated with diabetes, obesity, venous thromboembolism, high cholesterol, high blood pressure, and IBS, and there is a possibility of a small increased risk of skin cancer.***

What is low-dose naltrexone (LDN)?

At a standard dose of 50mg to 100mg approved by the FDA in 1984, LDN has been used for patients with opioid addiction. Scientists have found out that this pre-existing medication, when administered at low doses, may be used for a wide range of conditions. LDN Research Trust defines low-dose naltrexone (LDN) as “LDN is a safe, non-toxic and inexpensive drug that helps regulate a dysfunctional immune system”.****

Low-dose naltrexone (LDN) for managing symptoms of psoriasis and psoriatic arthritis

In smaller doses, low-dose naltrexone (LDN) blocks the opioid receptors for several hours. This creates a rebound effect of increasing endorphins and receptors by 300%. An increase in endorphins lasts all day, long after the naltrexone has left the system. Endorphins are natural peptides produced in many cells which regulate cell growth, and reduce inflammation and pain.*****

Low-dose naltrexone is becoming more widely used among providers to manage pain and inflammation related to many other conditions. Ask your doctor whether low-dose naltrexone (LDN) could be a good fit to manage the symptoms of your psoriasis.

About Valor Compounding Pharmacy

Valor Compounding Pharmacy™, Inc. is a multi-state licensed 503A facility housing both sterile and non-sterile laboratories, located in Berkeley, CA. Valor is a specialized pharmacy that makes custom medications to meet the unique needs of the individual patient. Our goal is to reinvent pharmacy from a reactive vendor to a proactive partner in patient health care. We do that by optimizing turnaround time, being data-driven, and reducing patient anxiety. Our focus is on non-sterile and sterile, hazardous, and non-hazardous compounded medication. We work with a network of providers, patients, health systems/institutions, and research scientists in multiple states in the United States.

Blog sources:

*https://www.psoriasis.org/about-psoriasis/

**https://www.psoriasis.org/about-psoriasis/

***https://knowyourskin.britishskinfoundation.org.uk/condition/psoriasis/

****https://ldnresearchtrust.org/what-is-low-dose-naltrexone-ldn

*****https://ldnresearchtrust.org/psoriasis-and-low-dose-naltrexone-paula-johnson?gclid=CjwKCAjwrNmWBhA4EiwAHbjEQFKnqeCJmYZ2Qzf2XQiPNid7keIwKYy_X5hLhQatz6F-dg6LoynLFRoC8lEQAvD_BwE